Fig. 3

Effect of MAPC-CM on in vitro tube formation. Representative images of HDMEC cells in tube-like structures, 24 h after seeding onto Matrigel (a). MAPC-CM encouraged endothelial cells to reorganise into 3D vessel structures at each time point until 72 h (b). Values are mean ± SEM of 3 independent experiments. n = 6. Statistical significance calculated by one-way ANOVA followed by Tukey test, where * = p < 0.05, ** = p < 0.01, *** = p < 0.001, ns = non-significant