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Table 3 SVF cells for diabetic foot and its pros and cons

From: Therapeutic application of adipose-derived stromal vascular fraction in diabetic foot

SVF cells for diabetic foot Pros and cons Citations
Separation methods Enzymatic digestion Simple and convenient; possible immune response [52]
[53]
Physical method Safety; long digestion time; low cell yield
Cell populations Multi-cellular components Wide source; without culture; safety; effective [57]
Mechanism Differentiation Direct action; directly involved in vascular reconstruction [61]
Paracrine action Secrete various cytokines; promote vascular remodeling [66, 69, 71]
Cytokine action Cytokine interaction; promote cell proliferation and migration [77]