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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways

Fig. 1

hBMSCs cultured in SHED-CM had enhanced cell proliferation. a Representative images of hBMSCs cultured in DMEM, SHED-CM. and hBMSCs-CM, and quantitative analysis of relative CFU number. b Cell cycle analysis of passage 3 (P3) and passage 8 (P8) hBMSCs cultured in DMEM, SHED-CM (P8-SHED-CM) and hBMSCs-CM (P8-hBMSCs-CM) after long-term expansion. Percentage (%) of hBMSCs undergoing the G0/G1 and S phases. *P < 0.05, ***P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512