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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis

Fig. 2

UC-MSCs decreased the frequency and ratio of PMN-MDSCs and M-MDSCs in SS-like NOD mice. a, b PMN-MDSCs (CD11b+Ly6G+Ly6Clow) and M-MDSCs (CD11b+Ly6G-Ly6Chi) were detected by flow cytometry in BM and PBMC from 4- and 12-week-old NOD mice. Ratio of PMN-MDSC (Ly6Clow)/M-MDSC (Ly6Chi) in c BM and d PBMC of 4- and 12-week-old NOD mice. e, f PMN-MDSCs and M-MDSCs were detected by flow cytometry in BM and PBMC from in UC-MSC transplantation and control NOD mice. Ratio of PMN-MDSC (Ly6Clow)/M-MDSC (Ly6Chi) in g BM and h PBMC of UC-MSC transplantation and control NOD mice. Error bars indicate SEM. *p < 0.05, **p < 0.01, ***p < 0.001, n = 5

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Stem Cell Research & Therapy

ISSN: 1757-6512