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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Dental follicle stem cells rescue the regenerative capacity of inflamed rat dental pulp through a paracrine pathway

Fig. 7

Inflammatory infiltration and Runx2 expression in an experimental pulpitis model of rats after direct pulp capping with rDFSC-CM. A–C The degree of inflammatory infiltration in rats with experimental pulpitis in which the pulp was directly capped with rDFSC-CM for 24 h was determined by HE staining. A, A1 Blank control group (× 10). B, B1 The infiltration of inflammatory cell in the αMEM + LPS group is indicated by a black arrow (× 10). C, C1 rDFSC-CM + LPS group (× 4). Representative images of three independent experiments are shown. D–F The expression of Runx2 in an experimental pulpitis model in rats after direct pulp capping with rDFSC-CM for 7 days was revealed by immunofluorescence staining (× 20). D, D1 Blank control group. E, E1 αMEM + LPS group. Capillary dilatation is indicated by red arrows. F, F1 rDFSC-CM + LPS group. Some of the cells were positive for Runx2 (yellow arrows). Representative images of three independent experiments are shown

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Stem Cell Research & Therapy

ISSN: 1757-6512