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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages

Fig. 6

DNMT1 activates the MAPK1/p-ERK1/2 axis by downregulating miR-214-3p, thereby promoting wound healing and skin regeneration in mice. a The expression levels of miR-214-3p in each group were detected by RT-qPCR. b Western blot analysis detected the phosphorylation levels of DNMT1 and ERK1/2 normalized to GAPDH in each group. c Epidermal regeneration and quantitative analysis of epidermal tissues in each group. d Immunofluorescence staining was used to detect wound healing growth factors in wound tissues of each group. n = 8 per group. *p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512