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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Reparative effect of mesenchymal stromal cells on endothelial cells after hypoxic and inflammatory injury

Fig. 2

MSC-HUVEC adhesion mechanism. a Schematic representation of the molecular mechanism for MSC and HUVEC interaction. b The expression of CD62e and CD106 is upregulated on HUVEC membrane after hypoxia and reoxygenation. c CD29 and CD44 adhesion molecule expression is increased on the surface of MSC after incubation with injured HUVEC. d The blockage of CD29 and CD44 inhibits the adhesion of MSC to injured HUVEC. Significance of the comparison between injured HUVEC and the effect of blocking CD29 and/or CD44 is shown (n = 5). Results are shown as mean ± SD. **p value < 0.01; *p value < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512