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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

Fig. 5

SIRT1-modified hUCMSCs attenuated peritoneal inflammation in PD-induced peritoneal damage. qRT-PCR was used to measure the mRNA levels of IL-6 (a), IL-1β (b), TNF-α (c), and MCP-1 (d) in the peritoneal omentum tissues from the indicated groups. e Western blot was used to measure the protein levels of IL-6, IL-1β, TNF-α, and MCP-1 in the indicated conditions, and the relative expressions were normalized to control (f). Data are presented as mean ± SD. n = 8 for each group. *p < 0.05, **p < 0.01, and ***p < 0.001 between the indicated groups

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