Fig. 2

Exo-HIF-1α upregulated the downstream proangiogenic factors in hypoxia-injured HUVECs. a-c mRNA expression levels of VEGF, Ang-1, and PDGF in HUVECs, respectively (n = 3). d–f Protein expression level of VEGF, Ang-1, and PDGF detected by ELISA in the conditioned medium of HUVECs, respectively (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001. NS, no significance