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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis

Fig. 2

Effect of BM-MSC and AD-MSC treatment on lesion progression in infected C57BL/6 mice. C57BL/6 mice were inoculated in the footpad with Leishmania amazonensis; treated either with PBS, BM-MSC, or AD-MSC; and had lesion development measured with calipers on a weekly basis. After 77 days, the mice were euthanized, and the parasite load of the paw was determined by limiting dilution. a Analysis of lesion progression. b Analysis of parasite load in the paw. Representative of four independent experiments. N = 8. Values show the mean ± standard deviation. *Significantly different from PBS (control group) (P < 0.05)

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