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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation

Fig. 4

Effect of MSC-TGF-β1 on macrophage phenotype in septic mice. a The expression of CD86+ macrophages and CD206+ macrophages in the lung of each group was detected by flow cytometry. b The expression of CD86+ macrophages and CD206+ macrophages in the liver of each group was detected by flow cytometry. c The expression of CD86+ macrophages and CD206+macrophages in the liver of each group was detected by flow cytometry (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). CLP, cecal ligation and puncture; MSC, mesenchymal stem cell; MSC-NC, mesenchymal stem cell carrying GFP; MSC-TGF-β1, TGF-β1 overexpressing MSC

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Stem Cell Research & Therapy

ISSN: 1757-6512