Fig. 3
Electrophysiological properties of hESC-CM graft tissue from three GCaMP3+ lines after transplantation into injured hearts. Optical mapping outcomes by experimental model (subacute versus chronic) for hESC-CMs derived from three different parental hESC lines. a Mean graft optical action potential durations at 90% repolarization (oAPD90). b Mean graft oAPD90 for these same experimental conditions after applying Fridericia’s rate correction. c Percentage of hESC-CM graft area visible from the epicardial surface in each recipient heart that showed 1:1 host-graft coupling during imaging at 2 weeks post-transplantation. d Mean graft area, expressed as the percentage of the injury area occupied by graft as viewed from the epicardial surface. e Mean graft conduction velocity. n = 3–5 hearts per condition, **p < 0.01, ***p < 0.001