Fig. 6

Cytokine detection in BLM-treated MLE-12 cells after MenSC coculture. a PCA analysis of three different groups (n = 3). b Differential cytokine expression shown as a heat map. Red, green, and black colors represent upregulated, downregulated, and unchanged expression, respectively (n = 3). c Cytokines of significantly expressed in three different groups (RANTES, GM-CSF, MIP-1γ, MCP-5, Eotaxin, CCL1, and GITR) are highlighted with red boxes and arrows (n = 3). d, e Significantly different results from GO (c) and KEGG pathway (d) analysis results. Three biological replicates undergoing independent experiments were performed