Fig. 8From: Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogelBiochemical and histological assessment of chondrogenic differentiation in the presence or absence of 39 μM BICA at day 28. a GAG produced by hBM-MSC-loaded hydrogels within conditioned media (CM) or within hydrogels (INT). b Total collagen content of hBM-MSC-loaded hydrogels. c Toluidine blue and Safranin-O & fast green staining. Data are presented as means ± SD (n = 3) (*p < 0.05, **p < 0.01, ***p < 0.001)Back to article page