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Table 1 Specifications of in vitro and in vivo photobiomodulation parameters

From: Transplantation of photobiomodulation-preconditioned diabetic stem cells accelerates ischemic wound healing in diabetic rats

Specifications of in vitro photobiomodulation

Laser type

Wavelength (nm)

Power (W)

Duration of each administration (s)

Energy density (J/cm2)

Laser beam diameter (cm)

Laser beam area (cm2)

Power density (W/cm2)

 Red

630

0.05

46, 92

1.2,2.4

1.56

1.91

0.0261

 Near infrared

810

0.05

46, 92

1.2,2.4

1.56

1.91

0.0261

Company

NILTVIR202 Noura Instruments, Tehran, Iran

Specifications of in vivo photobiomodulation

 Parameters

Dose and unit

 Peak power output

75 W

 Average power

0.001 W

 Power density

0.001 W/cm2

 Wavelength

890 nm

 Wavelength range of the device

890±10 nm

 Pulse frequency

80 Hz

 Spot size

1 cm2

 Diameter

1.12 cm

 Pulsed duration

180 ns

 Duration of exposure for each point

200 s

 Energy density

0.2 J/cm2

 Number of laser shootings in each session

9

 Energy densities for one session and for the total sessions

1.8 and 25.2 J/cm2

 PBM radiation scheduling

Immediately after surgery, 6 days per week, for 16 consecutive days

 Probe

L07

 Company

MUSTANG 2000, Technica Co., Russia