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Table 3 Clinical Trials involving tissue- and cell-based therapy approaches to promote fistula and tissue regeneration in the oropharynx

From: Regenerative medicine approaches for the management of respiratory tract fistulas

Condition

Intervention

ClinicalTrials.gov Identifier1

Tracheoesophageal fistula, bronchoesophageal fistula, tracheal fistula

Adipose-derived stromal vascular fraction for aero-digestive fistulae

NCT03792360

Bronchial fistula

Human amniotic epithelial cells for treatment of bronchial fistula

NCT02959333

Bronchopleural fistula

Umbilical cord mesenchymal stem cells for treatment of bronchopleural fistula

NCT02961725

Enterocutaneous fistula

Stromal vascular fraction for treatment of enterocutaneous fistula

NCT01584713

Dysphonia

Innovative treatment for scarred vocal cords by local injection of autologous stromal vascular fraction

NCT02622464

Vocal cord paralysis, unilateral

Injection laryngoplasty using autologous fat enriched with adipose-derived regenerative stem cells

NCT02904824

Hoarseness, dysphonia, aphonia, vocal fold; scar

A study of local administration of autologous bone marrow mesenchymal stromal cells in dysphonic patients with vocal fold scarring

NCT04290182

Vocal fold; scar

Pilot study of bone marrow stem cell treatment of patients with vocal fold scarring

NCT01981330

  1. 1Source: https://clinicaltrials.gov/, accessed July 2020