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Table 2 Proteome analysis of chemokines in muscle biopsies of dyW mice

From: Congenital muscular dystrophy-associated inflammatory chemokines provide axes for effective recruitment of therapeutic adult stem cell into muscles

Chemokine

Fold difference/controla

Time since birth, weeks

1

2

3

4

5

6

CCL21

3.4

2.1

3.8

6.0

6.4

4.7

CXCL13

1.5

0.2

0.7

2.7

1.3

0.6

CCL6

5.6

6.6

6.0

7.1

7.0

17.0

C5/C5a

6.8

6.3

23.1

12.3

6.8

14.0

CCL28

1.5

2.6

3.5

3.7

4.0

3.2

RARRES2

1.6

1.9

6.3

8.6

7.4

76.2

CCL27

9.7

6.6

10.3

19.6

8.0

14.2

CXCL16

2.5

1.8

2.5

3.0

2.7

4.1

CCL11

5.1

1.3

2.5

3.8

1.3

3.2

CX3CL1

53.6

1.2

1.4

4.4

1.6

2.2

IL-16

4.2

3.9

4.3

9.9

7.3

20.1

CXCL10

2.6

2.4

4.0

7.9

4.6

6.5

CXCL11

2.1

3.8

2.8

3.7

2.0

4.8

CCL2

6.5

5.5

4.2

9.5

5.5

15.2

CXCL1

7.4

6.3

7.3

10.8

5.1

12.5

CXCL5

2.0

1.0

4.9

6.0

1.7

2.5

CCL8

7.7

11.4

18.3

3.0

4.4

23.5

CCL12

5.5

5.1

4.0

8.0

5.7

11.3

CCL22

12.7

3.0

4.9

9.9

10.5

5.6

CXCL9

3.5

2.6

3.7

4.2

5.2

4.0

CC3/CCL4

14.6

2.2

4.3

3.9

8.5

13.0

CCL9/CCL10

11.5

15.0

41.2

10.6

14.2

47.3

CXCL2

5.4

1.6

8.1

1.5

3.3

3.1

CCL5

1.6

0.9

12.6

4.6

2.6

2.2

CXCL12

11.7

4.3

7.0

12.1

6.0

14.1

  1. aData represented as fold difference of dyW muscle vs muscle from age-matched wild-type counterpart (control). Each protein array was processed in an identical manner and the number represents an average of triplicate experiments from 5 pooled muscle biopsies. Fold difference does not reflect quantity