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Table 2 Proteome analysis of chemokines in muscle biopsies of dyW mice

From: Congenital muscular dystrophy-associated inflammatory chemokines provide axes for effective recruitment of therapeutic adult stem cell into muscles

Chemokine Fold difference/controla
Time since birth, weeks
1 2 3 4 5 6
CCL21 3.4 2.1 3.8 6.0 6.4 4.7
CXCL13 1.5 0.2 0.7 2.7 1.3 0.6
CCL6 5.6 6.6 6.0 7.1 7.0 17.0
C5/C5a 6.8 6.3 23.1 12.3 6.8 14.0
CCL28 1.5 2.6 3.5 3.7 4.0 3.2
RARRES2 1.6 1.9 6.3 8.6 7.4 76.2
CCL27 9.7 6.6 10.3 19.6 8.0 14.2
CXCL16 2.5 1.8 2.5 3.0 2.7 4.1
CCL11 5.1 1.3 2.5 3.8 1.3 3.2
CX3CL1 53.6 1.2 1.4 4.4 1.6 2.2
IL-16 4.2 3.9 4.3 9.9 7.3 20.1
CXCL10 2.6 2.4 4.0 7.9 4.6 6.5
CXCL11 2.1 3.8 2.8 3.7 2.0 4.8
CCL2 6.5 5.5 4.2 9.5 5.5 15.2
CXCL1 7.4 6.3 7.3 10.8 5.1 12.5
CXCL5 2.0 1.0 4.9 6.0 1.7 2.5
CCL8 7.7 11.4 18.3 3.0 4.4 23.5
CCL12 5.5 5.1 4.0 8.0 5.7 11.3
CCL22 12.7 3.0 4.9 9.9 10.5 5.6
CXCL9 3.5 2.6 3.7 4.2 5.2 4.0
CC3/CCL4 14.6 2.2 4.3 3.9 8.5 13.0
CCL9/CCL10 11.5 15.0 41.2 10.6 14.2 47.3
CXCL2 5.4 1.6 8.1 1.5 3.3 3.1
CCL5 1.6 0.9 12.6 4.6 2.6 2.2
CXCL12 11.7 4.3 7.0 12.1 6.0 14.1
  1. aData represented as fold difference of dyW muscle vs muscle from age-matched wild-type counterpart (control). Each protein array was processed in an identical manner and the number represents an average of triplicate experiments from 5 pooled muscle biopsies. Fold difference does not reflect quantity