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Table 3 Proteome analysis of chemokines in muscle biopsies of Col6a1−/− mice

From: Congenital muscular dystrophy-associated inflammatory chemokines provide axes for effective recruitment of therapeutic adult stem cell into muscles

Chemokine

Fold difference/controla

Time after CTX treatment, days

0

1

3

7

14

21

Ccl21

4.0

3.8

3.3

2.7

6.3

5.5

Cxcl13

1.1

1.1

1.1

1.1

1.1

1.1

Ccl6

1.3

1.2

1.1

0.9

2.0

1.6

C5/C5a

18.1

3.0

9.6

19.9

80.2

23.0

CCL28

1.1

1.2

1.1

1.2

1.1

1.3

RARRES2

8.4

1.5

3.0

4.8

7.7

6.0

Ccl27

13.9

3.2

8.3

5.5

6.0

3.0

SRPSOX

1.1

1.2

4.8

1.1

1.2

1.1

Ccl11

1.1

1.2

1.1

1.1

1.2

1.1

Cx3cl1

1.1

1.1

1.1

1.1

1.1

1.1

IL16

11.9

1.1

1.5

5.1

36.4

14.6

Cxcl10

10.5

39.6

45.6

10.2

1.1

1.1

Cxcl11

1.1

1.1

1.1

1.1

1.1

1.1

Ccl2

29.3

12.2

15.4

18.9

13.1

16.7

Cxcl1

1.2

1.1

1.1

1.2

1.1

1.2

Cxcl5

1.2

4.3

1.1

1.2

1.1

1.2

Ccl8

8.7

1.6

4.4

1.2

48.7

7.5

Ccl12

22.3

1.5

14.7

6.8

35.9

20.9

Ccl22

1.1

1.1

1.2

1.1

1.2

1.1

Cxcl9

1.1

1.1

1.2

1.1

1.2

1.1

Ccl3/Ccl4

1.1

1.1

1.2

1.1

1.2

1.1

Ccl9/Ccl10

0.9

1.3

1.1

0.9

5.4

1.6

Cxcl2

1.2

1.1

1.2

1.1

1.2

1.1

Ccl5

1.1

1.1

1.2

1.1

1.2

1.1

Cxcl12

42.6

38.4

182.8

47.7

45.6

47.7

  1. aData represented as fold difference of Col6a1−/− muscle vs muscle from age-matched wild-type counterpart (control). Each protein array was processed in an identical manner and the number represents an average of triplicate experiments from 5 pooled muscle biopsies. Fold difference does not reflect quantity