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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: hPMSCs protects against d-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling

Fig. 2

hPMSCs promote the expression of Nrf2-mediated antioxidant genes in CD4+ T cells from d-gal-treated mice. a The expressions of nucleoprotein and cytosolic protein of Nrf2 and its downstream target genes (GCLC, HO-1, CAT, and NQO1) in CD4+ T cells. b The protein level of total Nrf2. c The ratio of nuclear/cytoplasm Nrf2. d The mRNA expressions of Nrf2 in CD4+ T cells. e–h The protein level of Nrf2 downstream target genes GCLC, HO-1, CAT, and NQO1 in CD4+ T cells. j–m The mRNA expressions of GCLC, HO-1, CAT, and NQO1 in CD4+ T cells. Data represent the mean scores ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01 (n = 10 animals per group)

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Stem Cell Research & Therapy

ISSN: 1757-6512