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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: hPMSCs protects against d-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling

Fig. 3

hPMSCs upregulate the expression of Nrf2 via Akt/GSK-3β/Fyn pathway in CD4+ T cells from d-gal-treated mice. a Nuclear translocation of Nrf2 and Fyn were determined by immunofluorescent staining (bar = 10 μm). b The expressions of Akt/GSK-3β/Fyn pathway in CD4+ T cells. c The ratio of p-Akt/Akt. d The ratio of p-GSK-3β/GSK-3β. e The level of nuclear Fyn. Data represent the mean scores ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01 (n = 10 animals per group)

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Stem Cell Research & Therapy

ISSN: 1757-6512