Fig. 7

SMFs reduces dexamethasone (Dex)-stimulated osteoporosis in mice. a, b Representative 2D (a) and 3D (b) micro-CT images of femurs from control and Dex-treated mice with gradient SMF stimulation for 3 months. c–g Quantitative micro-CT analysis of BMD (c), BV/TV (d), Tb.N (e), Tb.Sp (f), and Tb.Th (g) in SMF-exposed mice after Dex injection. *P < 0.05, **P < 0.01, as indicated. n = 4–5 per group. h–j H&E staining (h) and quantification of number (i) and area (j) of adipocytes in distal femurs. Scale bar, 100 μm. n = 6 per group. k–l Representative images of OCN immunohistochemical staining (k) and quantification of number (l) of osteoblasts in distal femurs. Scale bar, 100 μm. *P < 0.05, **P < 0.01, as indicated. n = 5 per group. ns=not significant