Fig. 2
Comparison of lung functions in rats with PF. The photographs reveal that the rats in each group were examined for arterial blood oxygen saturation (SpO2) in their forelimbs on day 49 after BLM injury (a). Transplantation of HUMSCs increased SpO2 in rats with PF when compared to other treatment methods on day 49 (a). Weekly records suggested that the SpO2 level significantly decreased since day 7 after BLM damage. Except the BLM + HUMSCs group, the trend of reduced SpO2 persisted up to day 49 in other treatment groups (b). The respiratory frequency was captured within 2 s from day 0 to 49 from each group (c). Compared to other treatments, transplantation of HUMSCs alleviated respiratory rates in rats with PF (d). Rats were weighed every week for 7 weeks. The results showed that the transplantation of HUMSCs improved body weight of rats with PF (e). n = 12 or 13 in each group. ✽: vs the Normal group, p < 0.05. #: vs the BLM group, p < 0.05