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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Extracellular vesicles from hydroxycamptothecin primed umbilical cord stem cells enhance anti-adhesion potential for treatment of tendon injury

Fig. 7

Scheme of the production of HCPT-EVs that prevents tendon adhesion by inhibiting fibroblast viability, proliferation, and myofibroblast transformation. After hydroxycamptothecin priming of human umbilical mesenchymal stem cells (HUMSCs), endoplasmic reticulum (ER) stress was elicited and led to more encapsulation of ER stress effector protein into the secreted EVs, which enhanced the anti-viability, anti-proliferation, and myofibroblast transformation inhibitory potential of EVs

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Stem Cell Research & Therapy

ISSN: 1757-6512