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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Extracellular matrix-based biomaterials as adipose-derived stem cell delivery vehicles in wound healing: a comparative study between a collagen scaffold and two xenografts

Fig. 3

Macroscopic analysis (a) of the wounds (dashed yellow line) showed no complications nor scarring tissue during healing, all conditions reached wound closure after 14 days and hADSC accelerated the wound closure process. Quantification of wound closure (b) in the absence of hADSCs showed that the CT side of the XenoMEM™ induced significantly lower wound closure at day 7 in comparison to hADSC injection and at day 10 in comparison to sham and hADSC injection. The BM side of MatriStem™ BM also presented significantly lower wound closure than hADSC injection at day 10. Wound closure in the presence of hADSCs was significantly higher than the sham group for the hADSC injection and the CT side of MatriStem™ with hADSCs at day 7. The hADSC injection, the CT side of MatriStem™ with hADSCs and the BM side of XenoMEM™ with hADSCs showed significantly higher wound closure than sham at day 10. In comparison to hADSC injection, significantly lower wound closure was observed for the BM side of MatriStem™ and the CT side of XenoMEM™ at day 10. Data presented as average ± standard deviation (n = 6). Asterisk indicates a significantly (p < 0.05) lower value than the sham group, double asterisks indicate a significantly (p < 0.05) higher value than sham group and number sign indicates a significantly (p < 0.05) lower value than ADSC control

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Stem Cell Research & Therapy

ISSN: 1757-6512