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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Extracellular matrix-based biomaterials as adipose-derived stem cell delivery vehicles in wound healing: a comparative study between a collagen scaffold and two xenografts

Fig. 6

Immunohistochemistry analysis of sections (a) for CD31 (green) showed the formation of microvessels in all groups. DAPI (blue) staining (a) showed a homogenous dispersion of cells in the wound area in all conditions. Scale bars 100 μm. CD31 area quantification (b) showed no differences between groups in the absence of hADSC and in the presence of hADSC, a significantly higher area of CD31 in comparison to sham was observed in all groups and only the BM side of the XenoMEM™ showed significantly higher CD31 expression than the hADSC injection. Cell counting from DAPI stained sections (c) sections did not reveal any differences in cell density in the wounds between the groups in the absence or presence of hADSC. Data presented as average ± standard deviation (n = 6). Double asterisks indicate a significantly (p < 0.05) higher value than sham group, number sign indicates a significantly (p < 0.05) lower value than ADSC group and double number sign indicates a significantly (p < 0.01) higher value than ADSC group

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Stem Cell Research & Therapy

ISSN: 1757-6512