Fig. 5

Combined treatment of SCI with ENSCs and ChABC resulted in significant reductions in tissue pathology, as assessed by eriochrome cyanine staining. a–d Representative sagittal sections of the spinal cords from each treatment group harvested from animals sacrificed 16 weeks post-injury and stained for eriochrome C. e–h Summary data of cavity area (e, f) or injured tissue area (g, h) analysis. ENSC transplantation or ChABC application applied as single treatments did not significantly affect the cavity size or the area of injured tissue. However, in the combined treatment group, there was a significant decrease in both cavity area and the area of injured tissue compared to the non-treated group. Data are represented as mean ± s.e.m. *Indicates significance (p ≤ 0.05). Scale bar—a 500 μm