Fig. 4

PCA and heat map of chondroitin sulfate-related factors. PCA plots of the samples based on 10 chondroitin sulfate- (a), 56 inflammation- (c), 425 catabolism- (d), 459 metabolism- (e), and 169 matrix- (f) mapped gene names. Color scale: red (down-represented) to green (up-represented) through black. (b) Heat map for the chondroitin sulfate process-associated genes, constructed on the basis of protein abundance levels estimated by nLC-MS/MS in 3 ASC-CM (ASC-CM 1-3) and 3 ASC-EV (ASC-EV 1-3) samples. Principal component analysis (PCA) and heat maps were obtained using XLSTAT software. F1 and F2, factor 1 and 2