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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Allogeneic human umbilical cord Wharton’s jelly stem cells increase several-fold the expansion of human cord blood CD34+ cells both in vitro and in vivo

Fig. 4

Colony-forming units and primitive HSC gene expression. a Representative BFU-E, CFU-GEMM, and CFU-GM colonies of CD34+ cells cultured in control, hWJSC-CM, and hWJSCs for 7 days. b Note the significantly greater most primitive CFU-GEMM colonies from CD34+ cells expanded with hWJSCs as compared to controls. c Note significantly greater primitive HSC HoxB4 gene expression in CD34+ cells expanded with hWJSCs as compared to controls. d Note significantly greater primitive HSC HoxA9 gene expression in CD34+ cells expanded with hWJSCs and hWJSC-CM compared to controls. All values are expressed as mean ± SEM of 3 biological samples with 3 replicates for each sample. *p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512