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Table 1 Renal function parameter measurements at the end of the study (day 45)

From: Therapeutic potential of human induced pluripotent stem cells and renal progenitor cells in experimental chronic kidney disease

Parameters Groups
Sham CKD RPC hiPSC
Body weight change (g) 61.6 ± 36.2a − 23.6 ± 101b,c 56.7 ± 23 59.7 ± 14
Mean arterial pressure (mmHg) 127 ± 1 201 ± 23 172 ± 30 177 ± 37
CCr (mL/min) 1 ± 0.1 0.85 ± 0.1d 0.91 ± 0.5e 1.61 ± 0.5
RCCr (mL/min/day) 0.001 ± 0.003 0.01 ± 0.01 0.005 ± 0.01 0.002 ± 0.008
SCr (mg/dL) 0.6 ± 0.1f 1.06 ± 0.5 0.87 ± 0.24 0.85 ± 0.13
PT24h (mg/24 h) 10 ± 0.2g 44.5 ± 22.6 45.8 ± 30 36 ± 21
  1. Results are presented as mean ± SD. Abbreviations: SCr serum creatinine, RCCr rate of decline of CCr, PT24h 24-h proteinuria, CCr creatinine clearance, CKD chronic kidney disease, RPC renal progenitor cell, hiPSC induced pluripotent stem cell. ap < 0.05 vs. CKD; b,cp < 0.05 vs. RPC and hiPSC; dp < 0.05 vs. hiPSC; ep < 0.05 vs. hiPSC, CKD; fp < 0.01 vs. CKD; gp < 0.01 vs. CKD vs. RPC vs. hiPSC