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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6

Fig. 8

miR-27b-3p inhibited cell migration and expression of EMT-associated proteins in vitro. a miR-27b-3p level in three groups analyzed by qRT-PCR. b Effect of miR-27b-3p on the expression of EMT-related proteins occludin, Vimentin, N-cadherin, and α-SMA evaluated by Western blot analysis. c Immunofluorescence was further used to assess cell morphological alteration. d–e Effects of miR-27b-3p on the migration and wound-healing ability of ARPE19 cells. Statistics are presented as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512