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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and DKK1

Fig. 2

BMSC-EVs suppresses IPF in vivo. a–c HE staining (a), Masson staining (b), and Sirius Red staining (c) images of the lung tissues of mice with PF (× 200). d Hydroxyproline content in lung tissues of mice with PF. e, f The mRNA (e) and protein (f) expression of myofibroblastic markers, α-SMA, and collagen I in lung tissue of mice with PF measured by RT-qPCR and Western blot analysis. *p < 0.05 vs. PF mice treated with PBS; #p < 0.05 vs. PF mice treated with BMSC-EVs. Differences among groups were analyzed by one-way ANOVA (n = 8)

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Stem Cell Research & Therapy

ISSN: 1757-6512