Fig. 4
From: Exosomal microRNA-22-3p alleviates cerebral ischemic injury by modulating KDM6B/BMP2/BMF axis
High KDM6B expression exacerbates cerebral ischemic injury. a RT-qPCR analysis of KDM6B expression in neurons upon treatment of OE-KDM6B or si-KDM6B. b Western blot analysis determining transfection effect of OE-KDM6B, siRNA1, siRNA2, siRNA3, and their corresponding controls. c CCK-8 assay detection of viability of neurons after treatment with OE-KDM6B or si-KDM6B, or controls. d Flow cytometry detection of apoptosis after treatment of OE-KDM6B and si-KDM6B, or controls. e Western blot analysis of cleaved caspase 3, caspase 3, Bax, and Bcl-2 protein expression after treatment of OE-KDM6B or si-KDM6B, or controls, and the corresponding quantification. *p < 0.05, **p < 0.01, and ***p < 0.001. Measurement data were presented as mean ± standard deviation. The data among multiple groups were analyzed by ANOVA