Stem Cell Research & Therapy

Table 8 Degradation time of the scaffold materials

From: Differences of embedding adipose-derived stromal cells in natural and synthetic scaffolds for dermal and subcutaneous delivery

Scaffold	Origin	Degradation in vivo	Measured after
^aPEG [14]	Synthetic	70%	3 days
^aPEG /^bPNIPAM [14]	Synthetic	40%	3 days
^cCHPA / ^dGTA / ^ePDGF-BB [24]	Natural	40%	2 weeks
Laminin/alginate [18]	Natural	60%	6 weeks
^fPuraMatrix [20]	Synthetic	100%	8 weeks
^hMGC/ ^gDAT [28]	Natural	50%	12 weeks
ⁱMCS / ^gDAT [28]	Natural	75–80%	12 weeks
Scaffold	Origin	Degradation in vitro	Measured after
^cCHPA-^dGTA-^ePDGF-BB [24]	Natural	50%	20 days
Chitosan/gelatin + ^jbFGF [32]	Natural	65 ± 3.5%	1 week
^kPLGA and ^lOEG₉ [33]	Combinatory	70%	4 weeks
^kPLGA [34]	Synthetic	≈50%	6 weeks

^aPEG polyethylene glycol, ^bPNIPAM poly(N-isopropylacrylamide), ^cCHPA 4-hydroxyphenyl acetic acid, ^dGTA gelatin modified with tyramine, ^ePDGF-BB platelet-derived growth factor, ^fPuraMatrix PuraMatrix peptide hydrogel (BD Biosciences, Bedford, Massachusetts), ^gDAT decellularized adipose tissue, ^hMGC methacrylated glycol chitosan, ⁱMCS methacrylated chondroitin sulfate, ^jbFGF basic fibroblast growth factor, ^kPLGA poly (lactide-co-glycolide), ^lOEG₉ oligo (ethylene glycol) 400

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ISSN: 1757-6512

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