Fig. 6

miR-455-3p is used to treat CCl4-induced acute liver injury in mice. a Experimental procedure in mice. b H&E staining of liver specimens. c CD68 immunohistochemistry. d Biochemical assays of hepatic indexes. e Flow cytometry analysis of the ratio of CD14 + CD16+ or CCR2 + CD16+ monocytes in peripheral blood CD45+ T cells. f Levels of inflammatory cytokines, chemokines, and growth factors in serum. Data are presented as the mean ± SEM (error bars). N = 5 mice per group; *p < 0.05, **p < 0.01, and ***p < 0.001. NC, miR-455-3p agomir negative control; miR, miR-455-3p agomir