Fig. 1

UCMSCs or UCMSC-CM accelerates skin wound healing in diabetic mice. a Gross view of wounds treated with PBS, FBs, UCMSCs, or UCMSC-CM at days 0, 3, 7, and 14 post administration. b The rate of wound closure in wounds receiving different treatments at the indicated times. c Histological images (H&E staining) of wound sections treated with PBS, FBs, UCMSCs, or UCMSC-CM at day 14 post administration. Scale bar 100 μm. d Histological images of the capillary-like structures in wound bed tissues of different groups. Black arrowheads indicate the capillary-like structures. Scale bar 100 μm. e Quantitative analysis of capillary densities in wound bed tissue. n = 12 per group. *P < 0.05, **P < 0.01