Fig. 9

Effect of PEMF-induced conditioned medium (CM) on the apoptotic status of MSCs and chondrocytes. Chondrocytes (a) or MSCs (b) were treated with Staurosporin (SPN; 200 nM) in conjunction with supplementation with either CCM or PCM for 2 h. Apoptotic activity was determined by Caspase 3/7 activity and was presented as relative fluorescence units (RFU). Data shown represent means ± SD, n = 6 from 2 independent experiments. * denote significant differences compared to no Staurosporin treatment; # denotes significant differences compared to Staurosporin treatment alone and @ denotes significant differences relative to CCM