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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Multifaceted characterization of the signatures and efficacy of mesenchymal stem/stromal cells in acquired aplastic anemia

Fig. 8

UC-MSC transplantation effectively ameliorated the symptoms of AA mice. a The model of AA mice. b, c AA mice receiving UC-MSC transplantation showed reduced mortality and prolonged survival, along with alleviating body weight decline (normal mice: n = 5; irrigation mice: n = 5; AA mice: n = 5; AA+MSC: n = 5). d The hypocellularity of bone marrow in AA mice was rescued after UC-MSC transplantation (normal mice: n = 3; irrigation mice: n = 3; AA mice: n = 3; AA+MSC: n = 3). e Increased peripheral blood cell count including white blood cell (WBC), hemoglobulin, platelets (PLT), neutrophil cell, reticulocyte, and red blood cell (RBC) were observed in AA mice after receiving UC-MSC transplantation (normal mice: n = 3; irrigation mice: n = 3; AA mice: n = 3; AA+MSC: n = 3)

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Stem Cell Research & Therapy

ISSN: 1757-6512