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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Exosomal microRNA-144 from bone marrow-derived mesenchymal stem cells inhibits the progression of non-small cell lung cancer by targeting CCNE1 and CCNE2

Fig. 2

Silencing CCNE1 and CCNE2 inhibited proliferation, colony formation, and reduced the number of S phase-arrested cells cultured NSCLC cells. a Cell proliferation measured by EdU assay (× 200). b Number of colonies formed measured by colony formation assay. c Cell cycle progression detected by flow cytometry. d The expression of proliferation related factors assessed by western blot analysis. *p < 0.05 vs. A549 cells transfected with sh-NC. The above measurement data were expressed as mean ± standard deviation. Data among multiple groups were analyzed by one-way ANOVA, followed by a Tukey post hoc test. The experiment was repeated in triplicate

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