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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Targeted silencing of miRNA-132-3p expression rescues disuse osteopenia by promoting mesenchymal stem cell osteogenic differentiation and osteogenesis in mice

Fig. 7

Targeted silencing of miRNA-132-3p improves the hindlimb bone microstructure of HU mice. a The region of interest (ROI) was selected as marked with yellow color. 3D reconstruction of ROI was shown at the bottom row of the images. b Three-dimensional microstructure parameters of the ROI, including bone mineral density (BMD), relative bone volume (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular space (Tb.Sp), and trabecular pattern factor were analyzed. Values are shown as mean ± SD, n = 6. *P < 0.05. NS, no significant

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