Fig. 2

The evaluation of RvE1 on the dentin mineralization ability in the damaged pulp repair process. The Masson trichrome staining (A), the immunohistochemical staining and the quantification of DMP1 (B), and DSP (C) in the control group and the RvE1 application group. The collagen shows up in blue and celluloses in red. The yellow triangle represents the reparative dentin, and b, d, f, h higher magnification views of a, c, e, g (A). f, h, j, l Higher magnification views of the black triangle areas in panels e, g, i, k, and black arrows (f, h, j, l) indicate the positive signal, respectively (B, C). Right panel shows the quantitative measurements of integrated optical density (IOD)/area of DMP1 (B) and DSP (C). NC negative control, PC positive control, VC vehicle control, P pulp, D dentin, RD reparative dentin. *P < 0.05, **P < 0.01, ***P < 0.001, n = 10