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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats

Fig. 1

MSC and MSC-Exo characterization and exosomal miRNA profiles. hUC-MSCs were characterized by CD73, CD90, CD105 (a), CD45, CD34, and HLA-DR (b) expression by using flow cytometry. c Representative images and quantitative analysis of western blots to assess CD9, CD63, and β-actin expression in MSCs and MSC-Exo (n = 3). Data are represented as mean ± SD. d The morphology of exosomes detected by transmission electron microscopy (n = 3). Scale bar = 500 nm. e The diameters and concentrations of exosomes analyzed by the nanoparticle tracking method. f Top 20 miRNAs expressed in MSC-Exo. MSC mesenchymal stem cell, MSC-Exo MSC-derived exosomes. *p < 0.05; **p < 0.01

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