Fig. 6

MiR-223 reduced donor T cell migration to recipient mice spleens. The proportion of H2kb ⁺ CD4 and CD8 T cell in recipient mice spleens on day 7 was assessed by flow cytometry. Compared with NC and aGvHD group, H2kb ⁺ CD4 and H2kb ⁺ CD8 cell percentages in miR-223 group showed significant reduction (a). The average number of H2kb ⁺ CD4 and H2kb ⁺ CD8 cells in miR-223 group showed significant decline (b). Data were presented as mean ± SEM. Measured in three independent experiments, n = 7 per group. *P < 0.05, **P < 0.01