The angiogenic potential of CD271+ human adipose tissue-derived mesenchymal stem cells

Table 1 Expression changes in genes of interest in CD271+ AD-MSCs. Expression changes are presented as fold change in the CD271+ population compared to the CD271− population, by RNA sequencing analysis

Gene	Fold change	Adjusted p value	Gene function
ANGPT1	1.22	0.156	Vascular development and angiogenesis
ANGPT2	2.36	1.42E−16	Vascular remodelling, angiogenesis in combination with VEGF
VEGFA	1.34	0.00120	Vascular growth factor
HGF	2.31	2.27E−07	Angiogenic growth factor
IL10RA	0.18	7.55E−44	Inflammatory receptor
IL1B	0.17	2.36E−41	Key cytokine in adipose tissue
TNF	0.19	4.23E−24	Activates M1 macrophages in adipose tissue
WNT2	0.24	2.39E−75	Oncogenic gene

ANGPT1 angiopoietin 1, ANGPT2 angiopoietin 2, VEGFA vascular endothelial growth factor A, HGF hepatocyte growth factor, IL10RA interleukin 10 receptor A, IL1B interleukin 1B, TNF tumour necrosis factor, WNT2 Wingless-type MMTV integration site family, member 2

ISSN: 1757-6512