Fig. 6

Intraperitoneal administration of catalpol increased bone healing capacity in OVX calvarial defect rats. a–d Micro-CT images and analysis of calvaria defect of different groups of rats. e New bone formation was detected by sequential fluorescent labeling of calcein. Histological assessment of the defect area by f H&E staining and g Masson trichrome staining. The data are presented as means ± SEM. ^**p < 0.01 vs. SHAM group, ^##p < 0.01 vs. OVX group