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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Induced neural stem cell grafts exert neuroprotection through an interaction between Crry and Akt in a mouse model of closed head injury

Fig. 1

CHI mouse serum pre-treatment led to Akt activation in iNSCs. ad RT-QPCR was utilized to determine the expression of the Erk (a), P38 (b), Jnk (c), and Akt (d) genes in iNSCs among the PBS (iNSCs receiving PBS pre-treatment), HI-CHI (iNSCs receiving HI-CHI mouse serum pre-treatment), and CHI (iNSCs receiving CHI mouse serum pre-treatment) groups following treatment with CHI mouse serum for 45 min (n = 3/group; one-way ANOVA, **P < 0.01 versus PBS and HI-CHI groups, respectively). e Representative immunoblots depicting the levels of p-AKT and AKT in iNSCs among the three groups after CHI mouse serum treatment. fh Histograms showing the relative levels of p-AKT (f), AKT (g), and p-AKT/AKT (h) in iNSCs among the three groups following treatment with CHI mouse serum (n = 6/group; one-way ANOVA, ***P < 0.001 versus PBS and HI-CHI groups, respectively)

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