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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Co-culture of ASCs/EPCs and dermal extracellular matrix hydrogel enhances the repair of full-thickness skin wound by promoting angiogenesis

Fig. 6

Microscopic observation of postoperative skin regeneration. a Analysis of HE staining of the wound on the 14th day after the operation. The black arrow indicates the skin appendages formed in the ECM+A+E group. The red arrows show the newly formed blood vessels in each group, and the number of new blood vessels in the ECM+A+E group is significantly more than that in the other groups. b Quantitative analysis of regenerated skin scar thickness, *p < 005, ECM+A+E group compared with all other groups. c Masson staining of regenerated skin 14 days after surgery. d OD value of Col I and Col III in each group. Total amount of collagen fibers in each group.*p < .005, the ECM+A+E group compared to all other groups. e CD31 immunofluorescence detection of regenerated skin tissue. The blood vessels are shown by red fluorescence. The number of new blood vessels in the ECM+A+E group is significantly more than that of the other groups. f: Quantitative analysis of the number of regenerated blood vessels, *p < 005, compare ECM+A+E group with other groups

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Stem Cell Research & Therapy

ISSN: 1757-6512