Fig. 8

Bone regeneration evaluated by Masson’s trichrome and HE staining. a Masson’s trichrome staining was conducted to show the newly formed bone within the implanted constructs at 12 weeks postoperatively. b HE staining was conducted to show the newly formed bone within the implanted constructs at 12 weeks postoperatively. c Quantification analysis of new bone area fraction in different groups at 12 weeks (n = 6). *p < 0.05 compared to the Blank group, **p < 0.01 compared to the Blank group, ^#p < 0.05 compared to the Scaffold group, ^##p < 0.01 compared to the Scaffold group, ^&p < 0.05 compared to the S+Cell group, ^&&p < 0.01 compared to the S+Cell group