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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and enhances adipogenic versus osteogenic differentiation in human bone marrow mesenchymal stem cells by sponging miR-431-5p

Fig. 1

hsa_circ_0006859 in exosomes is upregulated in osteoporosis patients. a Heat map of circRNA microarray profile in osteoporosis patients (n = 3) and healthy controls (n = 3). b Exosomal hsa_circ_0006859 expression in patients with osteopenia or osteoporosis and in healthy controls. c The correlation between hsa_circ_0006859 expression and spine T-score. d The correlation between hsa_circ_0006859 expression and spine Z-score. e ROC curve analysis of exosomal hsa_circ_0006859 to differentiate osteopenia patients from healthy controls. f ROC curve analysis of exosomal hsa_circ_0006859 to differentiate osteoporosis patients from healthy controls. g ROC curve analysis of exosomal hsa_circ_0006859 to differentiate osteoporosis patients from osteopenia patients. h Expression levels of exosomal hsa_circ_0006859 between samples from OPO patients at diagnosis and samples from patients who received anti-osteoporotic treatment for 9 months

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Stem Cell Research & Therapy

ISSN: 1757-6512