Table 1 Baseline patient demographic and disease characteristics of the study population
Characteristics | Mesenchymal patients | Non-mesenchymal patients | P value | |
|---|---|---|---|---|
Number (%) | 83 | 131 | ||
Age (years), median (P25–P75) | 15.37 (11.77–19) | 12.89 (9.22–18.4) | 0.023 | |
Patient sex, n (%) | Male | 54 (65.1%) | 74 (56.5%) | 0.213 |
Female | 29 (34.9%) | 57 (43.5%) | ||
Donor sex, n (%) | Male | 41 (51.3%) | 51 (42.9%) | 0.244 |
Female | 39 (48.7%) | 68 (57.1%) | ||
Sex match status, n (%) | Sex-mismatched | 48 (60%) | 54 (45.4%) | 0.043 |
Sex-matched | 32 (40%) | 65 (54.6%) | ||
ABO match status, n (%) | ABO-mismatched | 30 (37.5%) | 46 (37.4%) | 0.988 |
ABO-matched | 50 (62.5%) | 77 (62.6%) | ||
Survival status, n (%) | Alive | 60 (72.3%) | 86 (65.6%) | 0.309 |
Dead | 23 (27.7%) | 45 (34.4%) | ||
Source of HSCT, n (%) | BM | 29 (34.9%) | 52 (39.7%) | 0.485 |
PB | 54 (65.1%) | 79 (60.3%) | ||
Acute GvHD, n (%) | No | 40 (48.2%) | 74 (56.5%) | 0.236 |
Yes | 43 (51.8%) | 57 (43.5%) | ||
Chronic GvHD, n (%) | No | 53 (63.9%) | 81 (61.8%) | 0.766 |
Yes | 30 (36.1%) | 50 (38.2%) | ||
Stem cell number in grafts | WBC (× 108/kg), median (P25–P75) | 8.12 (5.79–10.05) | 8.41 (6.27–9.32) | 0.758 |
MNC (× 108/kg), median (P25–P75) | 7.03 (3–8.07) | 6.80 (3.5–8.36) | 0.317 | |
CD3 cell (× 106/kg), median (P25–P75) | 213.22 (53–339) | 221.05 (75.8–314.8) | 0.836 | |
CD34 cell (× 106/kg), median (P25–P75) | 3.9 (2.5–6.1) | 3.4 (2.5–7.4) | 0.712 | |