Fig. 12

MSCs ameliorated the kidney inflammatory response in mice. The mRNA expression levels of the inflammatory-related genes TNF-alpha, IL-1β, and IL-6 in the sham+saline, sham+MSC, AAN-saline, and AAN-MSC groups were detected using qPCR analysis. qPCR analysis confirmed the downregulation of the inflammatory genes TNF-alpha, IL-1β, and IL-6 in the AAN-MSC group compared with the AAN-saline group. Data are presented as the means ± SEM (n = 8). *P < 0.05 for the comparison between AAN-saline and AAN-MSC mice